Panel discussion on...

Beauty from within and holistic trends

Trisha Sugarek MacDonald, PhD, MS
Market Development Manager
Akay Bioactives, an Oterra company

Member of AgroFOOD Industry Hi Tech's Scientific Advisory Board

In this Panel Discussion, several prominent companies within the food and nutraceutical ingredient industry have been invited to discuss about drivers and barriers of healthy lifestyle, focusing on global and regional consumer trends, scientific achievements, emerging delivery formats, use of AI technologies and the implementation of the United Nations sustainability goals.

1) One of the biggest shifts in beauty is the move away from purely cosmetic claims toward whole-person beauty, where appearance is connected to lifestyle, longevity, and overall wellbeing.

What we hear from the brands that we partner with is that their consumers are increasingly looking at skin, hair, and healthy aging through a wider biological lens, including stress, sleep, hormones, metabolism, inflammation, the microbiome, especially the gut-skin axis, and cellular aging. What I think is great is that beauty is no longer viewed as surface-level only. It is becoming a reflection of how well the body is functioning. And when you feel good, you look good.


Because of this, we are seeing more demand for clinically substantiated ingredients that support beauty outcomes through broader pathways. Brands are asking for studies that go beyond skin hydration or wrinkle appearance and connect beauty to mood, energy, fatigue, oxidative stress, inflammatory markers, metabolic health, immune resilience (senescence), and even cellular aging markers like telomere length, activity or attrition.


Over the next five years, I think beauty-from-within claims will become more science-backed and more holistic, with an even greater focus on natural ingredients that are plant-based. The focus will not only be on skin, hair, and nails, but also on longevity, resilience, and health at the cellular level.

Consumers are also more educated and skeptical. They want transparency, clean labels, and credible clinical substantiation. The brands that win will be the ones that can connect visible beauty, internal wellness, and strong scientific credibility.


2)  The rise of GLP-1 medications has opened an important conversation around rapid metabolic change and visible beauty outcomes. Hair loss and changes in facial appearance, sometimes referred to as “Ozempic skin,” were not well defined early on, but emerging pharmacovigilance data and clinical observations are bringing these concerns forward (1).


What we understand today is that GLP-1 use may be associated with non-scarring hair loss, most often telogen effluvium and androgenetic alopecia.1 From a skin perspective, rapid weight loss, loss of muscle tone, inadequate protein intake, hydration challenges, and potential impacts on fibroblasts and collagen dynamics can all contribute to reduced skin elasticity and volume loss, especially in areas like the cheeks, temples, and under the eyes (23). The result can be a more hollow, skeletonized or aged appearance, all of which are undesirable.


This creates a major opportunity for the nutricosmetic category to evolve beyond traditional beauty positioning and support individuals more holistically during periods of metabolic transition. In fact, many brands are now inquiring about GLP-1 supportive products and ingredients, including those that support skin integrity, stress resilience, sleep quality, inflammation balance, healthy aging, the gut microbiome, and metabolic wellness alongside aesthetic outcomes.


I also think consumers increasingly want solutions that help preserve vitality and confidence during these transitions, rather than focusing on appearance alone. The future of beauty and metabolic wellness will likely become much more interconnected, especially as research continues to expand around the gut-skin axis and microbiome.


3) What excites me most about the “well-beauty” movement is that consumers are recognizing how connected the body really is. Stress, poor sleep, inflammation, mood, metabolism, and gut health can all influence how we look, feel, and age.


The connection between beauty, wellness, and longevity continues to be an area of interest as the category moves toward a more holistic, inside-out approach to healthy aging. Plant-based bioactives are being explored for their potential role in this space, while formulation strategies are being evaluated to help address common challenges such as limited solubility, stability, and bioavailability. This research may help inform future innovation in beauty-from-within applications.


What makes this especially exciting is the clinical direction. Studies can evaluate benefits in both men and women over time, looking beyond traditional beauty-from-within endpoints to include areas such as cellular aging, inflammation, antioxidant status, metabolic health, and resilience.

Self-reported outcomes around skin appearance, aging perception, satisfaction, energy, fatigue, and vitality are also important. So, not just asking, “Does the skin look better?” But also asking, “Do you feel better, too?”


Personally, I think this is where the category is going: clinically substantiated, whole-person beauty solutions that connect visible appearance with internal wellness and healthy aging. For brands, this also creates opportunities to pair scientifically substantiated botanicals with established ingredients like collagen, soluble keratin, and hyaluronic acid to build more complete beauty and longevity platforms. The goal is to deliver benefits consumers can experience early, with outcomes that are felt from within and reflected in outer beauty.


4) For many years, topical beauty has been front and center in the nutricosmetic segment because it created rituals people enjoyed. For me, using topical beauty products is aspirational. I can often feel the benefits after just one use, whether that is smoother texture, better hydration, or simply feeling more refreshed. Plus, they give me the confidence to look as good on the outside as I feel on the inside.


That said, the ingestible beauty category is catching up and on. Consumers are looking for beauty-from-within products that are effective, but also enjoyable and easy to use every day. That is where functional beverages, gummies, powders, stick packs, and other modern formats become really exciting.


The challenge is that these products still have to deliver on the full consumer experience. Taste, texture, aroma, clean label, convenience, and compliance all matter, along with meaningful clinical dosing, ingredient stability, solubility, and shelf-life performance.


So, the opportunity is not just to create an ingestible beauty product. It is to create one that people actually want to take consistently and will deliver the clinically meaningful benefits consumers are looking for.


I think the future of ingestible nutricosmetics is very exciting, especially for companies that can combine the scientific efficacy with a sensory experience consumers will enjoy and can easily build into their daily routines.


This is also why we have recently introduced a dedicated Sustainability Manager within the company. The objective is to give sustainability a more structured framework, based on measurable tools, traceable data, and clear short-, medium-, and long-term objectives. In this way, sustainability becomes not only a value or a communication topic, but an operational and strategic process that can be monitored, improved, and integrated into ingredient development.


11) One of the biggest opportunities in women’s health and beauty is recognizing that menopause is not one single experience. Pre-, peri-, and post-menopause are biologically different stages, and women can experience them very differently depending on hormone patterns, stress, metabolism, lifestyle, and overall health.


That is what the industry has often missed. For too long, women’s formulas were treated as one-size-fits-all, when the needs of a woman in her early 30s may be very different from a woman navigating perimenopause, disrupted sleep, mood changes, hot flashes, or changes in sexual wellness and confidence. This is why precision matters. We need to design products around her life stage, her symptoms, and her desired outcome, not just a generic “women’s health” label.


That is where I think the category has an opportunity to evolve. Women are looking for solutions that work with their biology, not against it, and that support hormonal wellbeing in a more thoughtful and life-stage-specific way.


Rather than relying on a one-size-fits-all approach, the next generation of women’s health innovation should focus on supporting natural physiological pathways within healthy ranges, with solutions that are clinically substantiated and designed around real quality-of-life outcomes.


To me, this represents where the category needs to go: science-backed, stage-specific support that respects women’s biology and addresses the everyday experiences that matter most, from comfort and emotional wellbeing to sleep, vitality, and overall quality of life.

References and notes

Panelists

Vincenzo Zaccaria

Bionap (Active Group)

Trisha Sugarek MacDonald

Akay Bioactives, an Oterra company

Benny Antony

Arjuna Natural

Carlos Morales Ruiz

Aurora Intelligent Nutrition

Juliane Hellhammer

DAACRO

Franziska Schmitt

DAACRO

Annie Liu

DolCas Biotech

KG Rao

DolCas Biotech

Zachin Rao

DolCas Biotech

Miri Eliyahu

Euromonitor International

Magda Starula

Euromonitor International

Aarthi Janakiraman

Everest Group

Dieter Bracke

Fermedics BV

Mike Hughes

FMCG Gurus

Katia Merten-Lentz

Food Law Science and Partners

Oliver Wolf

Gelita

Silvia Pisoni

Gnosis by Lesaffre

David Foreman

Herbal Pharmacist Media

Lucilla Caricchio

Hylobates Consulting

Johanna Maukonen

IFF Health

Arthur C. Ouwehand

IFF Health

Serena Tongiani

Indena

Volker Spitzer

IQVIA Consumer Health

Stephanie Krammer-Lukas

IQVIA Consumer Health

Tyler Holstein

Kemin Human Nutrition and Health

Alison M. Winger

Key2Biotics

Karen E. Todd

Kyowa Hakko

Celia Martin

Lallemand Bio-Ingredients

Elodie Aragon

Lallemand Health Solutions

Chris Kilham

Medicine Hunter

Greg Cumberford

Natures Crops International

Pauline Cox

Sow & Arrow

Sybille Buchwald-Werner

Newday

Laetitia d’Ursel

People Science

Belinda Tan

People Science

Colleen Quinn

Colleen Quinn Consultancy

Matevž Ambrožič

PharmaLinea

Maja Orešnik

PharmaLinea

Lucia Barra

Probiotical

Annalisa Visciglia

Probiotical

Walter Fiore

ROELMI HPC

Florencia Moreno Torres

Rousselot

Shaheen Majeed

Sabinsa

Ilaria Campestri

B2B Health & Beauty,
ESG Industrial Processes Expert

Kelly Dobos

Consultant, Cosmetic Chemist

He Li

School of Food & Health
Beijing Technology & Business University

Claire Liu

Seppic

Suyin Perret-Gentil Robespierre

Suannutra

Jennifer Toomey

TopGum Industries

Inbal Nahmias

TopGum Industries

Anu Turpeinen

Valio