Panel discussion on...

Cognitive health

Karen E. Todd, RD
Kyowa Hakko USA

Member of AgroFOOD Industry Hi Tech's Scientific Advisory Board

In this Panel Discussion, several prominent companies within the food and nutraceutical ingredient industry have been invited to discuss about drivers and barriers of healthy lifestyle, focusing on global and regional consumer trends, scientific achievements, emerging delivery formats, use of AI technologies and the implementation of the United Nations sustainability goals.

Commentary article

 A 30-Year Journey in Cognitive Health: Innovations, Trends, and Future Directions

For over 30 years, I have dedicated my career to advancing cognitive health, driven by the conviction that our brain is our most vital asset. Every memory we cherish, every thought we form, and every decision we make depends on the well-being of this remarkable organ. Today, I am excited to share insights from global dietary supplement industry experts—including new perspectives from leading research and Q&A sessions—that illuminate emerging breakthroughs and evolving trends poised to redefine brain health for generations to come.

A Global Shift Toward Enhanced Brain Wellness

Recent data reveal that the use of nutritional supplements has surged worldwide, with consumer uptake climbing from 23% to 36% in just a few years. The brain health supplements market was valued at $8.63 billion in 2022, according to Grand View Research, with a projected 13.3% CAGR through 2030 . This trend underscores a broader shift: today’s consumers are not merely focused on preventing cognitive decline—they actively seek solutions to boost mental clarity, alleviate stress, and optimize performance. Whether it’s the Asia-Pacific market’s rapid adoption or Europe’s tailored memory-enhancing formulations, the global landscape reflects an urgent, unified drive toward better brain health.

Source: Grand View Research

Notably, younger demographics—from competitive gamers to busy professionals—are increasingly investing in cognitive supplements. They are no longer viewing brain health solely as an elderly concern but as a critical component of daily performance. As one expert noted, “Everyone with a brain should be considering a brain health ingredient,” a sentiment that has spurred product innovation across all age groups.

Bridging Tradition with Cutting-Edge Science

A recurring theme among industry experts is the successful fusion of time-tested natural ingredients with modern scientific innovation. Traditional botanicals like ginkgo biloba, ashwagandha, and Lion’s Mane are being reformulated using advanced delivery systems that enhance bioavailability. For instance, breakthroughs in liposomal and micellar encapsulation have dramatically increased the absorption of key nutrients—curcumin’s bioavailability, for example, can be boosted up to 375-fold, unlocking its full therapeutic potential.


Moreover, branded ingredients backed by rigorous clinical trials are building consumer trust. As highlighted in recent Q&A sessions, companies are investing heavily in substantiating claims with advanced research. One example, where a metabolomic study of citicoline has provided fascinating insights into gene expression changes that may signal future cognitive benefits. This dedication to research is transforming ingredients into trusted, high-quality components that consumers are willing to pay a premium for.

Personalization: Tailoring Brain Health to Individual Needs

Personalization is rapidly emerging as the gold standard in cognitive health solutions. Advances in genetic testing, microbiome research, and AI-driven analytics are enabling the creation of supplements tailored to individual needs. Whether it’s formulating for stress management in North American professionals, memory support for aging populations in Asia, or performance enhancement for competitive gamers, customized solutions are reshaping the market.


Data from multiple surveys underscore that consumers are increasingly seeking products that speak directly to their unique genetic profiles and lifestyles. Personalized approaches not only enhance efficacy but also empower consumers by providing transparency and traceability in their supplement choices.

Harnessing Technology and Tackling Digital Fatigue

Technological innovations are revolutionizing the field of cognitive health. AI and big data analytics now streamline clinical trials by enabling the efficient analysis of vast datasets from wearables and digital health tools. These insights help identify subtle, demographic-specific responses to cognitive supplements and optimize formulations for better outcomes.


At the same time, digital fatigue has emerged as a modern challenge. Constant screen exposure leads to mental exhaustion, reduced focus, and sleep disturbances. In response, some companies are developing dual-action products that support both cognitive function and eye health, while others are leveraging research on the gut-brain axis. For example, prebiotics like chicory root fiber are being explored for their potential to enhance memory and cognitive flexibility by modulating the gut microbiota.

Sustainability and Regulatory Nuances

Sustainability is now a critical factor in supplement production. Consumers demand ethically sourced, eco-friendly products that not only deliver on performance but also uphold environmental integrity. Manufacturers are adopting sustainable practices—from renewable botanical sourcing and upcycling by-products to minimizing packaging waste—to build long-term trust and align with consumer values.


Navigating an increasingly complex regulatory landscape remains a challenge. With diverse frameworks in Europe, North America, and Asia, companies must ensure that health claims are rigorously supported by scientific evidence and tailored to regional standards. For new market entrants, investing in robust research and transparent communication is essential to stand out in a crowded field.

Emerging Breakthroughs and the Future of Cognitive Health

The future of cognitive health supplements is both promising and dynamic. Recent breakthroughs in areas such as neuroinflammation, mitochondrial health, and the gut-brain axis are reshaping product development. Ingredients like citicoline continue to demonstrate broad efficacy across age groups, while novel compounds—including polyphenols, nootropic peptides, and fermented nutrients—are emerging as potent cognitive enhancers.


Looking ahead, the industry will likely see a surge in multi-benefit formulations that combine cognitive support with mood enhancement, energy, and immune function. Consumers are increasingly favoring holistic, convenient solutions such as functional beverages, gummies, and powders over traditional capsules. Moreover, personalized nutrition—powered by AI, genetic testing, and microbiome insights—will enable the precise tailoring of supplements to individual needs.


As one expert predicted, “Why take 10 supplements when a single or dual combination of nutrients can support various benefits?” This ethos of “less is more” is set to drive future innovation, making cognitive health supplements more accessible and effective for a broader population.

In Appreciation of Global Expertise

The insights shared by experts from all of these experts collectively paint a robust picture of the current state and future potential of cognitive health. Their collective expertise—from advanced research and personalized nutrition to innovative delivery systems and sustainability—provides a solid foundation for the evolution of this exciting field.


Reflecting on my 30-year journey, I remain inspired by the relentless pursuit of innovation that continues to drive our industry forward. The integration of cutting-edge science, personalization, and ethical practices is transforming cognitive health from a niche concern into a mainstream pillar of overall wellness. I extend my sincere gratitude to all the experts whose insights have enriched our understanding and helped pave the way for a future where every individual can enjoy a sharper, more resilient mind.