Panel discussion on...
Pet Supplements
Oliver Wolf
Product Promotion, Gelita

Member of AgroFOOD Industry Hi Tech's Scientific Advisory Board

Pet supplements at a turning point
Pet supplements are moving beyond their niche origins and are establishing themselves as a key pillar of proactive pet health, particularly in mobility and healthy ageing. Owners want solutions that keep their dogs and cats active and happy for longer, and they are increasingly willing to pay more for products that are both backed by science and easy to integrate into daily feeding routines. For marketing and R&D teams, this creates a sweet spot for specific Bioactive Collagen Peptides: recognizable, collagen-based, yet clearly positioned around joint comfort and quality of life rather than vague “wellness.”
Pet-specific research: why it matters for brands
Human joint health research provides a valuable starting point. However, true differentiation in the pet category comes from science generated in the target animal population. Brands that rely solely on human data risk sounding generic. Brands that invest in animal-specific validation build credibility, trust and long-term relevance. Specific Bioactive Collagen Peptides (BCP) were therefore tested directly on canine cartilage cells and in dogs with osteoarthritis, showing improved cartilage metabolism and better mobility in real-life conditions (1). For brand positioning, this allows you to talk about “dog-specific collagen peptides for joint cartilage metabolism” instead of making generic collagen promises that consumers increasingly question.
Pet Humanization: emotional driver, if expectations stay realistic
The humanization trend is not going away—pets are “fur family,” and owners want to support them with the same care they apply to their own health. This is a powerful emotional driver: joint-support concepts that echo human mobility solutions feel intuitive and approachable on pack and in communication. BCP fit neatly into this, because it they are pure collagen solution that consumers already associate with joint health, but tailored to pets and backed by in vivo studies in the target species. Credibility starts with realistic expectations. The goal is measurable improvements in mobility and activity over time—not immediate “miracles.” Positioning nutrition as supportive rather than curative strengthens consumer trust.
From bioavailability to bioactivity: what really convinces R&D
Many pet supplements still talk mainly about “high bioavailability,” but R&D teams know that being absorbed is only half the story. For cartilage health, the real value lies in bioactivity: can the ingredient actually trigger the right processes in the joint once it reaches the target tissue? BCP were developed around specific collagen peptide profiles that stimulate cartilage extracellular matrix (ECM) synthesis and help rebalance the breakdown–build-up cycle in joint tissue. This “designed for function” angle supports more concrete narratives such as “supports joint cartilage metabolism and mobility” and differentiates them from unspecific collagen that cannot demonstrate such targeted activity (2).
What kind of evidence is realistic today?
The pet supplement market is maturing, and regulators, vets and premium brand owners are all asking for stronger evidence. For joint health in particular, the current benchmark includes:
- Lab data showing how the ingredient acts on relevant cells or tissues (for example, canine chondrocytes for joint cartilage).
- In vivo trials in the target species, ideally double-blind, randomized and placebo-controlled.
- Clear, statistically significant outcomes on mobility and gait, accompanied by measurable improvements in quality of life within a realistic timeframe.
Canine studies with very specific collagen peptides have demonstrated increased cartilage matrix synthesis, reduced catabolic markers, and clinical improvements in gait and lameness after around 12 weeks of oral supplementation in dogs with osteoarthritis (3). For brand owners, this level of evidence supports credible on-pack and B2B claims without overstepping into drug territory.
Claims and labeling: reducing confusion, building trust
In a crowded marketplace, exaggerated health claims and imprecise language can quickly undermine credibility. Two pitfalls stand out:
- Confusing “bioavailability” with “bioactivity,” which can leave consumers impressed but misinformed.
- Using lifestyle phrases that sound scientific but are not backed by robust data.
For the collagen used, the focus should be on science-backed, structure–function style language: supporting joint cartilage metabolism, mobility, activity and overall quality of life. Differentiating “collagen peptides with proven effects in dogs” from “collagen-containing” products with no species-specific data can be a key trust builder in both professional and consumer communication. Transparent substantiation—a short summary of study design, duration and main outcomes in technical materials—supports regulatory discussions and gives marketing teams solid ground for storytelling.
Methodological challenges: working with real pets, not only lab models
Running high-quality clinical trials in the target species is demanding. Owners must consent, recruitment can be slow, and every animal comes with its own mix of breed, lifestyle and pre-existing conditions. To still generate meaningful results, the trials have been conducted in privately owned dogs with diagnosed osteoarthritis, using robust designs (double-blind, placebo-controlled) and objective tools like treadmill gait analysis alongside scoring systems. For R&D teams, this shows that it is possible to work under real-world conditions and still get publishable, decision-driving data—as long as endpoints and protocols are carefully chosen (1, 3) .
Owner vs vet assessments: two perspectives, one story
Owner feedback is highly relevant for market success because it reflects what buyers actually notice: is the dog willing to walk, climb stairs, play or jump into the car again? These “everyday” observations played an important role in our studies, where owners reported increased vitality over the course of supplementation. At the same time, veterinary assessments and gait analysis offer the objectivity needed for robust claims and R&D confidence. In trials with specific collagen peptides, veterinarians recorded continuing improvements in walk and agility, which matched owner impressions and strengthened the overall message. Combining both perspectives in study design makes the data more convincing for both technical and commercial stakeholders.
Healthy ageing and combination concepts: where the market is heading
One clear trend in pet nutrition is the move toward holistic healthy ageing, especially in dogs that remain active well into senior years. Pet owners are looking for “mobility plus” solutions that not only support joints but also comfort, recovery and overall vitality. This opens the door for smart combinations, for example pairing BCP — which supports joint cartilage metabolism and mobility — with complementary ingredients such as plant-based anti-inflammatory components like rose hip. For brand owners, such combinations enable differentiated premium concepts: a collagen-peptide “engine” for cartilage, surrounded by co-actives that address inflammation or oxidative stress, all under a clear, science-aligned mobility and healthy-ageing positioning.
In this Panel Discussion, several prominent companies within the food and nutraceutical ingredient industry have been invited to discuss about drivers and barriers of healthy lifestyle, focusing on global and regional consumer trends, scientific achievements, emerging delivery formats, use of AI technologies and the implementation of the United Nations sustainability goals.
Panelists
References and notes
- Schunck, M. , Louton, H. and Oesser, S. (2017) The Effectiveness of Specific Collagen Peptides on Osteoarthritis in Dogs-Impact on Metabolic Processes in Canine Chondrocytes. Open Journal of Animal Sciences, 7, 254-266. doi: 10.4236/ojas.2017.73020.
- Koivisto et al., 2014; Siebert et al., 2010
- The oral intake of specific Bioactive Collagen Peptides (BCP) improves gait and quality of life in canine osteoarthritis patients—A translational large animal model for a nutritional therapy option
Dobenecker B, Böswald LF, Reese S, Steigmeier-Raith S, Trillig L, et al. (2024) The oral intake of specific Bioactive Collagen Peptides (BCP) improves gait and quality of life in canine osteoarthritis patients—A translational large animal model for a nutritional therapy option. PLOS ONE 19(9): e0308378. https://doi.org/10.1371/journal.pone.0308378
Questions
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Ingredients companies - clinical data
A) What are the main scientific gaps that still exist in PET supplement development compared to human dietary supplements?
B) How important is species-specific research when selecting and developing active ingredients for pets? Can human data ever be sufficient?
C) Is the humanization of pets helping consumers make better-informed choices, or does it risk creating unrealistic expectations about supplement performance?
D) From an ingredient supplier’s perspective, which quality parameters (standardization, bioavailability, purity) are most critical for PET applications?
E) How are trends such as “clean label,” sustainability, and transparency influencing pet owners’ purchasing decisions in the PET supplement space?
F) What type of clinical evidence should realistically be expected to support PET supplement claims today?
G) Which types of claims are most likely to be misunderstood by consumers, and how can this risk be reduced through clearer substantiation and labeling?
H) What are the main methodological challenges in conducting clinical trials for companion animals, and how can they be addressed?
I) How reliable are owner-reported outcomes compared to veterinary assessments, and how should they be integrated into study design?
L) Have you noticed an increasing trend in the use of one (or more) ingredients for pet supplements formulated to promote healthy ageing?
Formulation
A) What are the biggest formulation challenges in PET supplements, particularly regarding palatability, stability, and dosing accuracy?
B) How do formulation choices (e.g., chews, powders, liquids) influence compliance and consistent use from a consumer perspective?
C) Do you see a shift toward simpler, single-ingredient formulations, or are multi-active blends still the dominant approach? Why?
D) How do species differences (dogs vs cats, size, age) influence formulation strategies?
E) Omega 3 alternatives for pet nutrition and sustainability: how do the innovative omega-3s for pet food stack up against their traditional fishy counterparts?
Regulation
A) How do regulatory frameworks for PET supplements differ between the EU and the US, and what challenges do these differences create for global brands?
B) Which types of claims represent the highest regulatory risk today, and which are more likely to be acceptable if properly substantiated?
C) Do you expect regulatory oversight of PET supplements to become stricter in the coming years? Why or why not?
D) What role should veterinarians play in guiding pet owners’ choices regarding PET supplements, and how can trust between brands, vets, and consumers be strengthened?
Open questions
A) Looking ahead 5–10 years, what will be the key factors determining the credibility and long-term success of the PET supplements sector?
B) In your view, what single change—scientific, regulatory, or educational—would most improve consumer trust in PET supplements over the next decade?
References and notes










